Z-Trp-OSu is a commonly used reagent, it is in the side chain of tryptophan with a protective effect of tert-butoxycarbonyl group, the formation of Z-Trp-OSu.
Z-Trp-OSu have the following characteristics and properties:
1. Appearance: white or white solid;
2. molecular formula: C25H24N2O6;
3. Molecular weight: 448.46g/mol;
4. melting point: 180-182°C;
5. Solubility: Z-Trp-OSu is soluble in some organic solvents (such as dimethyl sulfoxide), but almost insoluble in water.
Z-Trp-OSu is mainly used in the reaction of protecting hydroxyl functional groups in peptide synthesis. It can be used as an N-terminal activation reagent for amino acids and peptides for the formation of linked peptide sequences via amide bonds. Z-Trp-OSu has good stability, high selectivity and efficiency in the synthesis of peptides.
The method for preparing Z-Trp-OSu is generally obtained by reacting tryptophan with tert-butylchlorocarbonate. The specific preparation details may vary depending on the experimental conditions and requirements. It is recommended to prepare under suitable laboratory conditions.
Regarding safety information, although the toxicity and danger of Z-Trp-OSu are not high, the following points still need to be paid attention to during use:
1. may be irritating to the eyes, respiratory system and skin, avoid direct contact;
2. Use should wear protective gloves, eye protection and laboratory clothing to prevent inhalation or contact with skin;
3. avoid inhalation of dust, avoid ingestion;
4. Before use, you should understand and follow the relevant safety operation guidelines and chemical management regulations in detail.